| 1 | Founders Federal Credit Union | Lancaster, SC | $5.20B | 13.62% | 1.57% | 0.68% | 294,048 |
| 2 | South Carolina Federal Credit Union | North Charleston, SC | $2.59B | 13.34% | 0.97% | 0.60% | 157,780 |
| 3 | SRP Federal Credit Union | North Augusta, SC | $2.09B | 13.79% | 1.46% | 0.74% | 203,074 |
| 4 | Safe Federal Credit Union | Sumter, SC | $1.97B | 10.97% | 1.39% | 0.63% | 140,414 |
| 5 | Allsouth Federal Credit Union | Columbia, SC | $1.51B | 19.60% | 1.96% | 0.41% | 119,585 |
| 6 | Palmetto Citizens Federal Credit Union | Columbia, SC | $1.50B | 13.48% | 1.66% | 1.11% | 87,082 |
| 7 | S.C. State Federal Credit Union | Columbia, SC | $1.47B | 15.57% | 2.09% | 0.82% | 94,160 |
| 8 | Sharonview Federal Credit Union | Indian Land, SC | $1.33B | 7.63% | -0.23% | 1.18% | 81,582 |
| 9 | Rev Federal Credit Union | Summerville, SC | $1.24B | 13.75% | 0.41% | 0.57% | 66,744 |
| 10 | Family Trust Federal Credit Union | Rock Hill, SC | $805.4M | 11.85% | 1.20% | 0.73% | 60,145 |
| 11 | CPM Federal Credit Union | North Charleston, SC | $759.3M | 8.89% | -0.95% | 1.92% | 67,624 |
| 12 | Spero Financial Federal Credit Union | Greenville, SC | $701.5M | 8.30% | 0.23% | 0.94% | 45,560 |
| 13 | Greenville Federal Credit Union | Greenville, SC | $512.3M | 11.02% | 0.83% | 0.50% | 35,628 |
| 14 | Carolina Trust Federal Credit Union | Myrtle Beach, SC | $422.0M | 10.04% | 0.92% | 0.83% | 41,114 |
| 15 | MTC Federal Credit Union | Greenville, SC | $302.6M | 12.73% | 0.20% | 0.90% | 16,069 |
| 16 | SPC Credit Union | Hartsville, SC | $265.8M | 11.42% | 0.46% | 1.13% | 25,511 |
| 17 | Carolina Foothills Federal Credit Union | Spartanburg, SC | $224.3M | 12.02% | -0.18% | 1.30% | 19,427 |
| 18 | Georgetown Kraft Credit Union | Georgetown, SC | $191.9M | 18.67% | 1.90% | 0.95% | 18,425 |
| 19 | Mid Carolina Credit Union | Lugoff, SC | $181.8M | 12.69% | 0.67% | 0.66% | 13,968 |
| 20 | Greenville Heritage Federal Credit Union | Greenville, SC | $181.2M | 12.53% | 0.93% | 0.34% | 11,448 |
| 21 | Caro Federal Credit Union | Columbia, SC | $174.9M | 15.41% | 0.38% | 0.88% | 10,586 |
| 22 | Upstate Federal Credit Union | Anderson, SC | $148.5M | 9.77% | 1.13% | 0.26% | 17,889 |
| 23 | South Carolina National Guard Federal Credit Union | Columbia, SC | $98.3M | 26.61% | 2.35% | 0.13% | 5,544 |
| 24 | Santee Cooper Credit Union | Moncks Corner, SC | $95.9M | 15.01% | 1.29% | 0.97% | 7,218 |
| 25 | Curis Financial Credit Union | Columbia, SC | $84.3M | 23.49% | 0.47% | 0.59% | 9,129 |
| 26 | Latitude 32 Federal Credit Union | Charleston, SC | $69.5M | 14.83% | 1.78% | 0.39% | 6,368 |
| 27 | Nucor Employees' Credit Union | Florence, SC | $68.2M | 19.74% | 1.96% | 0.61% | 8,632 |
| 28 | Palmetto First Federal Credit Union | Florence, SC | $64.1M | 21.01% | 1.43% | 1.89% | 6,576 |
| 29 | Neighbors United Federal Credit Union | Greenwood, SC | $64.0M | 12.57% | -0.14% | 1.27% | 7,281 |
| 30 | Tru Federal Credit Union | Greenwood, SC | $63.4M | 11.01% | -0.27% | 0.42% | 7,403 |
| 31 | Secured Advantage Federal Credit Union | Simpsonville, SC | $55.7M | 12.18% | -0.47% | 0.88% | 4,404 |
| 32 | Dixies Federal Credit Union | Darlington, SC | $47.6M | 22.73% | 0.52% | 0.80% | 5,038 |
| 33 | Pee Dee Federal Credit Union | Florence, SC | $40.8M | 24.85% | 0.59% | 0.39% | 4,633 |
| 34 | Hopesouth Federal Credit Union | Abbeville, SC | $39.4M | 25.39% | 0.98% | 3.23% | 3,894 |
| 35 | Columbia Post Office Credit Union | Columbia, SC | $25.2M | 24.31% | 0.98% | 0.28% | 1,189 |
| 36 | S C I Federal Credit Union | Florence, SC | $23.6M | 14.24% | -0.11% | 0.36% | 1,544 |
| 37 | Edisto Federal Credit Union | Orangeburg, SC | $23.4M | 17.37% | 0.14% | 1.54% | 2,771 |
| 38 | Berkeley Community Federal Credit Union | Moncks Corner, SC | $16.6M | 19.70% | 2.46% | 5.60% | 2,103 |
| 39 | Anmed Health Federal Credit Union | Anderson, SC | $16.5M | 14.29% | 1.02% | 0.08% | 2,515 |
| 40 | Self Memorial Hospital Federal Credit Union | Greenwood, SC | $14.0M | 10.00% | 0.96% | 1.19% | 1,827 |
| 41 | Emerald Credit Association Federal Credit Union | Greenwood, SC | $10.3M | 8.39% | 0.38% | — | 1,193 |
| 42 | South Carolina Methodist Conference Credit Union | Columbia, SC | $5.6M | 8.58% | 0.06% | 0.25% | 984 |
| 43 | Brookland Federal Credit Union | West Columbia, SC | $5.1M | 11.25% | -0.84% | 3.19% | 1,161 |
| 44 | S.C.H.D. District 7 Federal Credit Union | Orangeburg, SC | $4.9M | 17.70% | -2.02% | 7.50% | 540 |
| 45 | Trinity Baptist Church Federal Credit Union | Florence, SC | $2.3M | 16.83% | 1.44% | 0.20% | 196 |