Branch Presence
Banks with Branches in Saint Louis, MO
Stifel Bank and Trust is the biggest bank in Saint Louis, MO, with $17.53B in deposits at its Saint Louis branches, 27.0% of the city's total as of the June 30, 2026 FDIC Summary of Deposits. U.S. Bank N.A. has the most branches here, with 22.
45 banks operate 157 branches in Saint Louis, MO, ranked below by local branch count from the FDIC Summary of Deposits. This counts every bank with a branch here, not only banks headquartered locally.
Deposit share is each bank's share of the $64.98B held in Saint Louis, MO, as of the June 30, 2026 FDIC Summary of Deposits, ranked by deposits (#1 is largest). Banks that book deposits at a headquarters branch can show a share that exceeds their local customer base.
| Bank | Branches in Saint Louis | Local deposits | Deposit share |
|---|---|---|---|
| U.S. Bank N.A. | 22 | $10.47B | 16.1% (#3) |
| Bank of America, N.A. | 12 | $10.44B | 16.1% (#4) |
| Commerce Bank | 10 | $916.0M | 1.4% (#7) |
| Simmons Bank | 8 | $774.5M | 1.2% (#11) |
| Regions Bank | 8 | $368.9M | 0.6% (#16) |
| JPMorgan Chase Bank, N.A. | 8 | $228.1M | 0.4% (#21) |
| Midwest Bankcentre | 7 | $776.6M | 1.2% (#10) |
| Midland States Bank | 7 | $301.7M | 0.5% (#17) |
| Great Southern Bank | 7 | $156.4M | 0.2% (#24) |
| PNC Bank, N.A. | 6 | $385.2M | 0.6% (#15) |
| Royal Banks of Missouri | 6 | $276.9M | 0.4% (#18) |
| First Bank | 6 | $234.8M | 0.4% (#20) |
| Busey Bank | 5 | $673.3M | 1.0% (#13) |
| BMO Bank N.A. | 3 | $678.5M | 1.0% (#12) |
| The Central Trust Bank | 3 | $216.8M | 0.3% (#22) |
| Enterprise Bank & Trust | 3 | $70.0M | 0.1% (#33) |
| Stifel Bank and Trust | 2 | $17.53B | 27.0% (#1) |
| UMB Bank, N.A. | 2 | $2.13B | 3.3% (#5) |
| Carrollton Bank | 2 | $454.3M | 0.7% (#14) |
| Commercial Bank | 2 | $166.4M | 0.3% (#23) |
| First Mid Bank & Trust, N.A. | 2 | $102.7M | 0.2% (#28) |
| Southern Bank | 2 | $89.8M | 0.1% (#30) |
| Lindell Bank & Trust Company | 2 | $89.6M | 0.1% (#31) |
| Stifel Bank | 1 | $13.67B | 21.0% (#2) |
| Saint Louis Bank | 1 | $922.0M | 1.4% (#6) |
| CIBC Bank USA | 1 | $898.5M | 1.4% (#8) |
| Stifel Trust Company N.A. | 1 | $850.4M | 1.3% (#9) |
| Sterling Bank | 1 | $276.5M | 0.4% (#19) |
| Midwest Regional Bank | 1 | $133.4M | 0.2% (#25) |
| FCB Banks | 1 | $130.8M | 0.2% (#26) |
| St. Johns Bank & Trust Company | 1 | $114.7M | 0.2% (#27) |
| The Northern Trust Company | 1 | $93.0M | 0.1% (#29) |
| American Bank of Freedom | 1 | $79.1M | 0.1% (#32) |
| Cass Commercial Bank | 1 | $55.8M | <0.1% (#34) |
| State Bank | 1 | $50.0M | <0.1% (#35) |
| The Huntington National Bank | 1 | $45.8M | <0.1% (#36) |
| Bank of Springfield | 1 | $41.3M | <0.1% (#37) |
| Montgomery Bank | 1 | $30.9M | <0.1% (#38) |
| Associated Bank, N.A. | 1 | $25.4M | <0.1% (#39) |
| Peoples National Bank, N.A. | 1 | $23.6M | <0.1% (#40) |
| Bank Star | 1 | $10.2M | <0.1% (#41) |
| Edward Jones Trust Company | 1 | $500K | <0.1% (#42) |
| EverBank, N.A. | 1 | — | — |
| Wells Fargo Bank, N.A. | 1 | — | — |
| CIBC National Trust Company | 1 | — | — |
County deposit market: St. Louis, MO
The $48.49B held across 55 FDIC-insured banks in this county, as of the June 30, 2026 FDIC Summary of Deposits. The 10 largest are shown; see every bank in the St. Louis, MO market with its change from a year earlier. Banks only: credit unions are not in the Summary of Deposits.
| Rank | Bank | Deposit share | Deposits | Branches |
|---|---|---|---|---|
| 1 | Commerce Bank | 12.5% | $6.04B | 22 |
| 2 | Bank of America, N.A. | 12.4% | $6.02B | 19 |
| 3 | U.S. Bank N.A. | 12.2% | $5.93B | 31 |
| 4 | Enterprise Bank & Trust | 9.2% | $4.44B | 7 |
| 5 | Regions Bank | 5.9% | $2.87B | 22 |
| 6 | PNC Bank, N.A. | 5.5% | $2.67B | 14 |
| 7 | First Bank | 4.6% | $2.24B | 16 |
| 8 | Midwest Bankcentre | 3.7% | $1.79B | 9 |
| 9 | The Central Trust Bank | 3.1% | $1.51B | 10 |
| 10 | Cass Commercial Bank | 2.2% | $1.06B | 2 |
Metro area deposit market: St. Louis, MO-IL
The $141.72B held across 111 FDIC-insured banks in this metro area, as of the June 30, 2026 FDIC Summary of Deposits. The 10 largest are shown; see every bank in the St. Louis, MO-IL market with its change from a year earlier. Banks only: credit unions are not in the Summary of Deposits.
| Rank | Bank | Deposit share | Deposits | Branches |
|---|---|---|---|---|
| 1 | U.S. Bank N.A. | 13.0% | $18.36B | 73 |
| 2 | Stifel Bank and Trust | 12.4% | $17.53B | 2 |
| 3 | Bank of America, N.A. | 11.8% | $16.72B | 32 |
| 4 | Stifel Bank | 9.6% | $13.67B | 1 |
| 5 | Commerce Bank | 5.8% | $8.23B | 38 |
| 6 | Enterprise Bank & Trust | 3.9% | $5.48B | 16 |
| 7 | Regions Bank | 3.7% | $5.19B | 59 |
| 8 | PNC Bank, N.A. | 2.4% | $3.40B | 28 |
| 9 | Carrollton Bank | 2.1% | $2.98B | 11 |
| 10 | UMB Bank, N.A. | 2.1% | $2.94B | 14 |
Banks in Saint Louis: common questions
What is the biggest bank in Saint Louis, MO?
Stifel Bank and Trust is the biggest bank in Saint Louis, MO, with $17.53B in deposits at its Saint Louis branches, 27.0% of the city's total as of the June 30, 2026 FDIC Summary of Deposits. U.S. Bank N.A. has the most branches there, with 22.
How many banks are in Saint Louis, MO?
45 FDIC-insured banks operate 157 branches in Saint Louis, MO as of the June 30, 2026 FDIC Summary of Deposits. This counts every bank with a branch in the city, not only banks headquartered there. Credit unions are not in the Summary of Deposits.
What are the largest banks in Saint Louis, MO?
Ranked by deposits held in Saint Louis branches as of the June 30, 2026 FDIC Summary of Deposits: 1. Stifel Bank and Trust (27.0%); 2. Stifel Bank (21.0%); 3. U.S. Bank N.A. (16.1%); 4. Bank of America, N.A. (16.1%); 5. UMB Bank, N.A. (3.3%). The share is each bank's part of all deposits in the city.
Largest banks in Missouri
For the state as a whole, see the largest banks in Missouri, ranked by total assets and by deposits in Missouri branches, or every bank in the Missouri bank directory.
Banks in other Missouri cities:
About this data
Branch counts and local deposits come from the FDIC Summary of Deposits, the annual June 30 survey of branch-office deposits for every FDIC-insured bank. Click any bank to see its full regulatory profile and complete branch network. Looking for banks headquartered here instead? See the US bank directory.