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Profitability · Mississippi

US Banks with Highest Return on Assets (ROA) in Mississippi

Ranked among banks headquartered in Mississippi. Re-ranked 1-58 within the state from the same national ranking population.

#1 Return on Assets (ROA): FNB PICAYUNE BANK — 3.11% . Return on Assets (ROA) measures net income divided by average total assets — the single most-watched US banking profitability metric.

Ranked: 58 banks with reported data Showing: Top 58 Source: FFIEC call reports (Q1 2026) What is this metric? See the US Banks with … glossary entry Go deeper: ROA vs. ROE for Banks: Profitability Ratios Explained
# Bank HQ US Banks with … Total Assets
1 FNB Picayune Bank Picayune , MS 3.11% $279.2M
2 Peoples Bank Mendenhall , MS 2.85% $503.4M
3 Commerce Bank Corinth , MS 2.54% $164.6M
4 Jefferson Bank, the Greenville , MS 2.35% $202.5M
5 Citizens Bank Columbia , MS 2.33% $486.2M
6 Priorityone Bank Magee , MS 1.92% $1.19B
7 First Southern Bank Columbia , MS 1.86% $309.0M
8 Riverhills Bank Vicksburg , MS 1.83% $447.1M
9 Farmers and Merchants Bank Baldwyn , MS 1.72% $567.1M
10 Bna Bank New Albany , MS 1.63% $841.4M
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11 First Bank Mccomb , MS 1.49% $558.4M
12 Citizens National Bank of Meridian, the Meridian , MS 1.46% $1.88B
13 Bankokolona Okolona , MS 1.43% $349.3M
14 Bankplus Belzoni , MS 1.40% $8.28B
15 Renasant Bank Tupelo , MS 1.40% $27.09B
16 First Security Bank Batesville , MS 1.39% $932.8M
17 Bank of Holly Springs, the Holly Springs , MS 1.36% $597.4M
18 Covington County Bank Collins , MS 1.35% $108.8M
19 Bank of Brookhaven Brookhaven , MS 1.32% $266.5M
20 Trustmark Bank Jackson , MS 1.26% $18.98B
21 Planters Bank & Trust Company Indianola , MS 1.22% $2.69B
22 Bank of Forest Forest , MS 1.22% $298.1M
23 Century Bank Lucedale , MS 1.20% $562.2M
24 Bank of Commerce Greenwood , MS 1.16% $1.16B
25 United Mississippi Bank Natchez , MS 1.13% $563.1M
26 Bank of Anguilla Anguilla , MS 1.11% $199.4M
27 Cadence Bank Tupelo , MS 1.09% $53.53B
28 Bankfirst Financial Services Macon , MS 1.08% $3.32B
29 Bank of Kilmichael Kilmichael , MS 1.07% $344.3M
30 Cleveland State Bank, the Cleveland , MS 1.03% $345.7M
31 Peoples Bank, the Ripley , MS 1.02% $582.2M
32 Community Bank of Mississippi Flowood , MS 1.02% $5.12B
33 Merchants and Planters Bank Raymond , MS 1.00% $207.2M
34 Pike National Bank Mccomb , MS 0.95% $405.1M
35 Guaranty Bank and Trust Company Belzoni , MS 0.92% $3.01B
36 Copiah Bank Hazlehurst , MS 0.91% $331.6M
37 First National Bank of Clarksdale Clarksdale , MS 0.88% $392.8M
38 Story Bank Dba Story Financial Partners Jackson , MS 0.85% $957.0M
39 Commercial Bank, the De Kalb , MS 0.83% $286.5M
40 Citizens Bank and Trust Company Marks , MS 0.83% $105.4M
41 Bank of Franklin Meadville , MS 0.83% $303.3M
42 Bank of Winona Winona , MS 0.81% $142.6M
43 FNB Oxford Bank Oxford , MS 0.80% $931.2M
44 Bank of Yazoo City Yazoo City , MS 0.79% $326.0M
45 Peoples Bank, Biloxi, Mississippi, the Biloxi , MS 0.72% $787.9M
46 Citizens Bank of Philadelphia, the Philadelphia , MS 0.68% $1.53B
47 Great Southern Bank Meridian , MS 0.62% $342.8M
48 Bank of Wiggins Wiggins , MS 0.60% $233.6M
49 Hancock Whitney Bank Gulfport , MS 0.57% $35.53B
50 First Federal Savings & Loan Association of Pascagoula-moss Point Pascagoula , MS 0.43% $377.6M
51 Unity Bank of Mississippi Holly Springs , MS 0.38% $288.0M
52 First State Bank Waynesboro , MS 0.34% $949.8M
53 Grand Bank for Savings, F.S.B. Hattiesburg , MS 0.30% $276.3M
54 Merchants & Marine Bank Pascagoula , MS 0.15% $960.8M
55 The First Bank Hattiesburg , MS 0.02% $7.93B
56 First Choice Bank Pontotoc , MS -0.24% $558.7M
57 Magnolia State Bank Bay Springs , MS -3.62% $465.6M
58 Holmes County Bank Lexington , MS -12.66% $151.9M

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All data sourced from the most recent FFIEC call report filings, refreshed each quarter as new filings are processed. This leaderboard excludes banks with total assets under $100,000K to filter out anomalous micro-bank ratios. See /data-updates/ for the current data freshness window.

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